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本文报道日本广岛医科大学泌尿科,对前列腺癌患者长期用特大剂量合成雌激素治疗后,肝功能变化的观察。病例系任意选择的42例有组织学诊断,但无明显肝脏转移的前列腺癌病人,均属不能手术的 C 和 D 期。病人施行睾丸切除术。1年治疗按反应分成二组:第一组反应良好:30例,年龄52～83岁,平均70.7岁。第二组反应差:12例,年龄50～83岁,平均65.1岁。治疗采用每日静滴5%葡萄糖水
This article reports the urology department of Hiroshima Medical University in Japan, and observes the changes of liver function after long-term use of a large dose of synthetic estrogen in patients with prostate cancer. The cases were randomly selected 42 cases of histological diagnosis, but no significant prostate cancer patients with liver metastasis were inoperable C and D stages. Patients undergo orchiectomy. One-year treatment was divided into two groups according to response: The first group responded well: 30 cases, aged 52 to 83 years, with an average of 70.7 years. The second group had poor response: 12 cases, aged 50 to 83 years, mean 65.1 years old. Treatment uses daily intravenous 5% glucose water