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中年男性患者,临床表现为腰部疼痛,椎体多发骨折,大量蛋白尿伴血清肌酐升高,无低蛋白血症和高脂血症,伴有高钙血症和高尿酸血症,免疫固定电泳发现单克隆λ轻链,骨髓穿刺明确多发性骨髓瘤,肾活检组织学为急性间质性肾炎,未见典型骨髓瘤管型,结合临床,考虑骨髓瘤相关肾损害。
Middle-aged male patients, the clinical manifestations of lumbar pain, vertebral fractures, a large number of proteinuria with serum creatinine increased, without hypoproteinemia and hyperlipidemia, accompanied by hypercalcemia and hyperuricemia, immune fixation Electrophoresis found that monoclonal λ light chain, bone marrow puncture clear multiple myeloma, renal biopsy histology of acute interstitial nephritis, no typical myeloma type, combined with clinical, consider myeloma-related renal damage.