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目的探讨多发性骨髓瘤常见误诊的原因。方法1994～2005年诊治的多发性骨髓瘤共43例,其中误诊32例,回顾性分析这32例病人的误诊原因。结果误诊率为74%,病人最常见的首发症状为骨痛,共28例次,发生率为87.5%,其次症状为肾脏病变,发生率71.9%,其他依次为贫血、感染、血小板减少等。结论被延迟诊断主要因首发症状及临床表现的多样性,所以对中老年人不典型的临床表现,应高度警惕多发性骨髓瘤的可能性。
Objective To investigate the causes of misdiagnosis of multiple myeloma. Methods A total of 43 cases of multiple myeloma were diagnosed and treated from 1994 to 2005, of which 32 cases were misdiagnosed. The causes of misdiagnosis in these 32 cases were retrospectively analyzed. Results The misdiagnosis rate was 74%. The most common initial symptom of patients was bone pain, with a total of 28 cases, the incidence rate was 87.5%. The second symptom was kidney disease with the rate of 71.9%. The others were anemia, infection and thrombocytopenia. Conclusion The diagnosis of delayed onset is mainly due to the first symptom and the diversity of clinical manifestations. Therefore, we should be highly alert to the possibility of multiple myeloma in the atypical clinical manifestations of middle-aged and elderly people.