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癌症病人唾液亚硝酸（ＮＯ２－）浓度大于１０ｐｐｍ者比正常人多一倍，证明ＮＯ２－同癌症有关。应用维生素Ｂ１（ｖｉｔａｍｉｎＢ１）或ＫＣｌＯ３改良的硝化培养基证明人体细菌（特别是肠菌）能将ＮＨ４＋硝化成ＮＯ２－。ＮＯ２－同二级胺合成亚硝胺就有致癌危险。用ＮＯ２－高产的Ｇ＋球菌喂小白鼠，能诱出癌前病变及乳癌。证明体内硝化能致癌。我们在７０００±人群中实验找出有轻微消化道症状和唾液ＮＯ２－三天都大于１０ｐｐｍ者应用抗菌素和抗亚硝胺药作防癌实验，经９年防癌观察，本法可使癌患病率下降５８．４％，效果明显。提示根据内源性ＮＯ２－和亚硝胺设想进行防癌是可行的。
Cancer patients had more than double the concentration of salivary nitrous acid (NO2 -) in the blood than normal subjects, demonstrating that NO2 is associated with cancer. The use of vitamin B1 (vitamin B1) or KClO3 modified nitrification media has demonstrated that human bacteria (especially enterobacteria) can nitrate NH4+ to NO2-. NO2-synthetic nitrosamines with secondary amines pose a cancer risk. Feeding mice with NO2-producing G+ cocci can induce precancerous lesions and breast cancer. Proved that in vivo nitrification can cause cancer. We used the antibiotics and anti-nitrosamines as anti-cancer experiments in the 7000± population to identify patients with mild gastrointestinal symptoms and saliva NO2 - more than 10ppm for three days. After 9 years of anti-cancer observation, this method can make cancer patients The rate of illness decreased by 58.4% and the effect was obvious. This suggests that anti-cancer therapy based on the idea of endogenous NO2- and nitrosamines is feasible.