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目的：探讨口服乙酰唑胺（ＡＣＺ）脑血液断层显像在脑血管疾病中的应用价值。方法：对１５例短暂性脑缺血发作患者进行静息和口服ＡＣＺ负荷脑血流显像，显像剂为９９ｍ Ｔｃ－乙撑双半胱氨酸二乙酯（ＥＣＤ）。结果：根据多兴趣区半定量分析结果，将对ＡＣＺ的脑血流反应分为：Ａ 型：皮质区域药前后局部脑血流量（ｒＣＢＦ）都正常（２４６）处；Ｂ型：静息ｒＣＢＦ正常，用药后出现新的减低区（２３）处；Ｃ型：静息ｒＣＢＦ减低，用药后更明显（１２）处及无明显变化（８）处；Ｄ型：静息ｒＣＢＦ减低，用药后改善（１１）处。结论：口服ＡＣＺ脑血流断层显像可观察脑血流变化，发现隐匿病灶，有利于脑血管疾病诊治
Objective: To investigate the value of oral acetazolamide (ACZ) in cerebral blood flow imaging. Methods: Fifteen patients with transient ischemic attack were subjected to resting and oral ACZ-loaded cerebral blood flow imaging. The imaging agent was 99m Tc-ethylene bis-cysteine diethyl ester (ECD). Results: Based on the results of semi-quantitative analysis of multiple regions of interest, the cerebral blood flow responses to ACZ were divided into: type A: normal cerebral cortical blood flow (rCBF) in the cortical area was normal (246); type B: resting rCBF normal , With a new reduction zone (23) after treatment; type C: reduced resting rCBF after treatment (12) and no significant change (8); type D: reduced resting rCBF and improvement after treatment 11) office. Conclusion: Cerebral blood flow changes can be observed by oral ACZ cerebral blood flow tomography, found hidden lesions, is conducive to the diagnosis and treatment of cerebrovascular disease