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传统右心室非生理性起搏可导致室内和室间电机械不同步,进而增加心力衰竭和心房颤动的风险。希氏-浦肯野系统起搏是生理性起搏的研究热点。希氏束起搏的阈值高、植入困难等因素限制了其应用和普及。近年来,国内学者提出了左束支区域起搏(LBBP)方式。且大量研究已证实左束支起搏的安全性和可行性。左束支起搏沿着传导系统下传,有效实现心室的电机械同步,同时,左束支起搏还具有电学参数良好稳定、明显改善心功能、可跨越阻滞部位起搏等诸多优势,将成为未来生理性起搏的重要发展方向。本文旨在对LBBP的起源、标准及分类、优势和局限性等进行综述。“,”Traditional right ventricular pacing is non-physiological pacing, can lead to ventricular electrical and mechanical dyssynchmnization, which increases the risk of heart failure and atrial fibrillation. His-Purkinje system pacing is the hot research of physiological pacing method. The high thresholds and difficult implantation of his bundle pacing limits its application and popularization. In recent years, domestic scholars have proposed left bundle branch area pacing. Many studies have confirmed the safety and feasibility of left bundle branch area pacing. Left bundle branch pacing transmit down the conduction system, which can effectively achieve ventricular electrical and mechanical synchrony, At the same time, it also has many others advantages, such as good and stable electrical parameters, significantly improved cardiac function, and pacing across blocked parts. It will become the main development direction of physiological pacing in the future. This article aims to review the origin, standard and classification, advantages and limitations of left bundle branch area pacing.