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本研究探讨钙粘连素与粘着物介导的生长抑制直接相关性。本研究显示N-钙粘连素在CHO细胞中有效地表达抑制细胞生长速度。这些细胞和另外二种成纤维细胞系相互作用在细胞产生血清性兴奋作用以后,引导细胞生长终止于G1期。这二种成纤维细胞系含有表面覆有N-钙粘连配体(重组体N-钙
This study explored the direct relevance of cadherin to adhesion-mediated growth inhibition. This study shows that N-cadherin efficiently expresses the inhibitory rate of cell growth in CHO cells. These cells interact with two other fibroblast cell lines to induce cell growth to terminate in the G1 phase after the cells produce serotonergic effects. These two fibroblast lines contain cells surface coated with N-cadherin ligand (recombinant N-calcium