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对45例外科治疗的结肠癌病人的术前血中癌胚抗原水平、肿瘤的组织病理学及术后临床经过进行了比较。肿瘤组织病理学观察包括肠壁受累的深度(按 Dukes分类),癌细胞的组织分化(按 Broder 氏分级),原发肿瘤内及其周围的淋巴细胞及浆细胞的浸润,血管、淋巴、神经周围的侵犯。结果显示所有上述指标,包括血清癌胚抗原水平在内,均对判断预后有价值。
The preoperative serum carcinoembryonic antigen level, histopathology, and postoperative clinical course of 45 patients with colon cancer undergoing surgery were compared. Tumor histopathological observations included depth of intestinal wall involvement (by Dukes classification), histological differentiation of cancer cells (by Broder’s scale), infiltration of lymphocytes and plasma cells in and around the primary tumor, blood vessels, lymph, nerves Infringement around. The results showed that all of the above indicators, including serum carcinoembryonic antigen levels, were valuable in determining prognosis.