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目的探索卵巢癌二线化疗方案。方法选择曾接受过肿瘤细胞减灭术及多疗程联合化疗、体检或影像学检查有可测得的肿瘤存在、一个月内无化疗史、未接受过放疗、血象及肝肾功正常、病理证实的卵巢上皮性复发癌患者作为治疗对象。用顺铂或卡铂与异环磷酰胺联合化疗，美施钠解毒。结果４８例病人中无完全缓解者；部分缓解１４例（２９２％）；稳定２２例（４５８％）；无效１２例（２５０％）。不同程度毒副反应病人可以耐受。结论顺铂或卡铂与异环磷酰胺联合化疗可作为卵巢上皮性复发癌补救治疗中的主要手段之一，且副反应病人可以耐受。
Objective To explore ovarian cancer second-line chemotherapy. Methods The patients who had undergone cytoreductive surgery and multiple courses of combined chemotherapy were included in the study. There were measurable tumors in the physical examination or imaging examination, no chemotherapy history within one month, no radiotherapy, normal blood and liver and kidney function, and pathological evidence Of ovarian epithelial recurrence cancer patients as the treatment object. With cisplatin or carboplatin and ifosfamide combined with chemotherapy, the United States Shi detoxification. Results 48 cases of patients without complete remission; partial remission in 14 cases (29 2%); stable in 22 cases (45 8%); ineffective in 12 cases (25 0%). Different degrees of toxicity of patients can tolerate. Conclusions Combination chemotherapy of cisplatin or carboplatin and ifosfamide can be one of the main means of remedial treatment for epithelial ovarian cancer recurrence, and patients with side effects can tolerate it.