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目的评价氧氟沙星滴耳液治疗急性化脓性中耳炎的疗效。方法 150例急性化脓性中耳炎患儿,随机分为对照组及观察组,各75例。对照组采用硼酸冰片滴耳液治疗,观察组采用氧氟沙星滴耳液治疗。比较两组的疗效、听力改善程度和药物起效时间。结果观察组总有效率96.00%高于对照组86.67%,差异有统计学意义(χ~2=4.127,P<0.05)。观察组听力改善程度为(7.7±2.3)d B、药物起效时间为(6.1±1.2)d,均优于对照组的(3.2±0.8)d B、(8.9±2.1)d,差异均有统计学意义(P<0.01)。结论氧氟沙星滴耳液用于治疗急性化脓性中耳炎疗效显著。
Objective To evaluate the efficacy of ofloxacin ear drops in the treatment of acute suppurative otitis media. Methods A total of 150 children with acute suppurative otitis media were randomly divided into control group and observation group, with 75 cases each. The control group was treated with boric acid borneol ear drops, and the observation group was treated with ofloxacin ear drops. The curative effect, hearing improvement and drug onset time were compared between the two groups. Results The total effective rate in observation group was 96.00%, which was significantly higher than that in control group (χ ~ 2 = 4.127, P <0.05). The degree of hearing improvement in the observation group was (7.7 ± 2.3) d B and the onset time of the drug was (6.1 ± 1.2) d, both of which were better than those of the control group (3.2 ± 0.8) d B and (8.9 ± 2.1) d respectively Statistical significance (P <0.01). Conclusion Ofloxacin ear drops for the treatment of acute suppurative otitis media significant effect.