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应用脉酶试验检查了８８例无胃症状的口腔门诊病人和９７例有胃症状而行胃镜检查的病人牙菌斑，并与相应的胃窦粘膜检查结果进行了对比研究。结果发现有胃症状组的牙菌斑脲酶试验阳性率（８６．６％）略高于无胃症状组（７５．０％），且出现阳性结果所需时间亦明显短于无胃症状组（Ｐ＜０．００１）。胃镜检查显示胃窦粘膜豚酶试验阳性率仅为４４．３％，明显低于牙菌斑。５２例（５３．６％）组织学检查发现幽门螺旋杆菌，１级１３例豚酶试验１０分钟阳性率者仅为２３．１％，而２、３级的３９例中，１０分钟阳性者高达７９．５％（Ｐ＜０．００１）。结果提示，口腔是幽门螺杆菌的另一重要生存环境，与胃幽门螺旋杆菌感染有关。
88 cases of oral outpatients without stomach symptoms and 97 cases of gastroscopy with gastric symptoms were examined by venous urease test and compared with the corresponding results of antral mucosal examination. The results showed that the positive rate of dental plaque urease test in gastric symptom group was slightly higher than that in non-gastric symptom group (75.0%, 86.6%), and the time required for positive results was also shorter than that in non-gastric symptom group P <0.001). Gastroscopy showed antral gastritis mucosal enzyme test positive rate was only 44.3%, significantly lower than the plaque. 52 cases (53.6%) histological examination found that Helicobacter pylori, grade 1 13 cases of bulldoze enzyme-positive 10-minute test was only 23.1%, while 2,3 in 39 cases, 10-minute positive up to 79.5% (P <0.001). The results suggest that the oral cavity is another important living environment of Helicobacter pylori, Helicobacter pylori infection with the stomach.