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亮菌甲素是从假蜜环菌(亮菌)中提取的、对胆道系统具有活性的成分之一。麻醉犬静脉注射本品后能松弛总胆管末端括约肌的紧张度,同时能使肝脏分泌胆汁量明显增加。麻醉大白鼠十二指肠给药或肌内注射本品后,均能促进肝脏分泌胆汁。麻醉犬静脉注射本品后还能引起十二指肠松弛、血压降低、心率减慢,作用均轻度而短暂。小白鼠腹腔注射和口服本品的急性LD_(50)分别为980mg/kg和>5000mg/kg。以人用每天最高剂量的25~125倍分别肌内注射于大白鼠和狗,每天一次,连续三个月,结果未见到明显的毒副作用。
Brilliant A is a member of the biliary system that is extracted from the Fungus (Fungi). Anesthetic dog intravenous injection of this product can relax the tension of the sphincter of the common bile duct, while enabling the liver to significantly increase the amount of bile secretion. Anesthetized rats duodenum or intramuscular injection of this product, can promote liver secretion of bile. Anesthetic dog intravenous injection of this product can also cause duodenal relaxation, blood pressure, heart rate slowed, the role of both mild and transient. The acute LD 50 of mice injected intraperitoneally and orally was 980mg / kg and> 5000mg / kg, respectively. The human daily maximum dose of 25 ~ 125 times intramuscularly in mice and dogs, once a day for three consecutive months, the results showed no significant side effects.