中国药典1977年版眼膏剂通则中,要求制备眼膏剂应在清洁避菌的环境中进行。应置避光、灭菌的容器中密封贮存,除检查颗粒细度外,并无对溢漏的检查项目。为此,我们参阅美国药典20版的方法,对国内部分眼膏剂进行了溢漏试验。 1.测定方法:任取供试品10支,用干布擦净管的外部,将管子按水平位置放在滤纸上, Chinese Pharmacopoeia 1977 edition of ointment General rules, the preparation of eye ointment should be carried out in a clean environment. Should avoid light, sealed containers sealed sterile storage, in addition to check the particle size, there is no spill inspection items. To this end, we refer to the United States Pharmacopoeia 20 version of the method, the domestic part of the eye ointment spill test. 1. Determination: Take any of the test 10, with a dry cloth to wipe the outside of the tube, the tube on the horizontal position on the filter paper,