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目的探讨急性时相蛋白与小儿脓毒症肝损伤的关系。方法脓毒症组50例,普通感染组30例,健康小儿组30例。入选病例入院后立即检测血清TF、PA、AB、ALT。结果血清TF、PA与ALT相关系数分别为:r=-0.506,r=-0.613(P<0.05),回归方程为:PA=187.457-1.393 ALT;TF=2.941-0.021 ALT。结论血清TF、PA与小儿脓毒症肝损伤有一定的相关性。
Objective To investigate the relationship between acute phase protein and liver injury in children with sepsis. Methods 50 cases of sepsis group, 30 cases of common infection group, 30 healthy children group. Selected patients admitted to hospital immediately after testing for serum TF, PA, AB, ALT. Results The correlation coefficients of serum TF, PA and ALT were r = -0.506 and r = -0.613 (P <0.05) respectively. The regression equation was: PA = 187.457-1.393 ALT; TF = 2.941-0.021 ALT. Conclusion Serum TF, PA and liver injury in children with sepsis have a certain correlation.