对3例先天性胆管扩张症合并胆管结石,利用 X 线衍射仪及红外线吸收光谱仪检测结石样品,发现3例结石成分基本一致,结晶程度极好,晶态物质的主要成分为柠檬酸钙、硬脂酸钙。结石属特殊型结石。作者认为,结石成因可能与胰胆管合流异常、胰液返流、胰脂肪酶被激活有关。同时对比观察2例遗传性球形细胞增多症合并胆囊结石的成分、类型与前者不同。指出胰胆管合流异常、胰液返流在结石形成过程中的作用值得重视。 Three cases of congenital bile duct dilatation associated with bile duct stones, the use of X-ray diffraction and infrared absorption spectroscopy detection of stone samples found that the three stones are basically the same composition, the degree of crystallization is excellent, the main components of crystalline material is calcium citrate, hard Calcium adipate. Stone is a special type of stone. The author believes that the causes of stones may be an abnormal pancreaticobiliary confluence, pancreatic reflux, pancreatic lipase is activated. At the same time, 2 cases of hereditary polycythemia complicated with gallstones were observed and compared with the former ones. Pointed pancreaticobiliary duct anomalies, pancreatic reflux in the formation of stones in the role worthy of attention.