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目的探讨血浆D-二聚体(DD)、免疫球蛋白检测在肺炎支原体肺炎(MPP)中的临床意义。方法选取2010年3月~2014年6月期间汕头中心医院确诊治疗的MPP患儿84例作为MPP组,同期选取体检中心健康儿童10例作为健康组,采用免疫比浊法检测免疫球蛋白、DD表达水平。结果 MPP组Ig G、Ig M、DD水平明显高于健康组,差异有统计学意义(P<0.05);在Ig G、Ig M、DD水平方面,重度组>中度组>轻度组,差异有统计学意义(P<0.05)。结论 DD、免疫球蛋白与MPP的发生、发展有关,可作为评估患者病情变化的参考指标。
Objective To investigate the clinical significance of detecting plasma D-dimer (DD) and immunoglobulin in Mycoplasma pneumoniae pneumonia (MPP). Methods From March 2010 to June 2014, 84 cases of MPP diagnosed and treated in Shantou Central Hospital were selected as MPP group. Ten healthy children were selected as healthy group in the same period. Immune turbidimetry was used to detect immunoglobulin, DD The expression level. Results The levels of Ig G, Ig M and DD in MPP group were significantly higher than those in healthy group (P <0.05). The levels of Ig G, Ig M and DD in severe group were significantly higher than those in mild group The difference was statistically significant (P <0.05). Conclusions DD and immunoglobulin are related to the occurrence and development of MPP and can be used as a reference index to evaluate the changes of patients’ condition.