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目的了解内江市艾滋病患者抗病毒治疗后生存时间现状,探讨不同治疗方案及基线CD4+T淋巴细胞计数对生存时间的影响。方法利用国家艾滋病综合防治信息系统抗病毒治疗内江市治疗数据信息,使用SPSS 17.0进行相关分析。结果本研究纳入227例患者,截止到2011-12-31,共有40例研究对象死亡,其中92.5%(37/40)死于艾滋病相关疾病。含AZT方案/d4T方案患者生存率差异无统计学意义,基线CD4+T淋巴细胞计数不同,患者的生存期差异有统计学意义(χ2=10.631,P<0.01)。结论定期监测艾滋病感染人群的CD+4T淋巴细胞计数,定期随访观察他们的临床症状,早期对患者开展抗病毒治疗更有利于延长病人的生存时间。
Objective To understand the survival time of patients with AIDS in Neijiang City after antiviral therapy and to explore the influence of different treatment regimens and baseline CD4 + T lymphocyte count on survival time. Methods Using the national AIDS integrated information system antiviral therapy Neijiang treatment data, using SPSS 17.0 for correlation analysis. Results A total of 227 patients were enrolled in this study. By December 31, 2011, a total of 40 subjects died, of which 92.5% (37/40) died of AIDS-related diseases. There was no significant difference in survival rate between patients with AZT and d4T regimen. The baseline CD4 + T lymphocyte counts were different, and the difference was statistically significant (χ2 = 10.631, P <0.01). Conclusion Regular monitoring of CD + 4T lymphocyte count in HIV-infected people and regular follow-up to observe their clinical symptoms, early treatment of patients with antiviral therapy is more conducive to prolong the survival time of patients.