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为探讨含服硝酸甘油(NTG)介入~(99m)Tc-甲氧基异丁基异腈(MIBI)心肌断层显像在心肌存活估测中的价值,对16例心肌梗塞患者先行常规静息态~(99m)Tc-MIBI 心肌断层显像,48小时后在静脉注入放射性药物前5分钟舌下含服 NTG0.6mg,然后再行服药静息态心肌断层显像。冠状动脉旁路移植术或经皮穿刺腔内冠状动脉成形术后3个月重复静息态心肌显像并进行对比分析。结果:16例患者静息态心肌断层显像有113个节段放射性分布异常,NTG 介入后有32个节段灌注改善,其中25个节段术后静息态心肌显像灌注亦改善;NTG 介入后灌注无变化或异常加重的81个节段,术后有66个节段灌注亦无变化或异常加重。NTG 介入心肌断层显像对存活心肌的预测准确率为80.5%。故含服 NTG 对提高静态~(99m)Tc-MIBI 心肌断层显像估测心肌存活有一定的临床价值,且方便易行,安全可靠。
To investigate the value of NTG intervention ~ (99m) Tc-methoxyisobutylisonitrile (MIBI) myocardial perfusion imaging in the estimation of myocardial viability, 16 patients with myocardial infarction before normal resting state ~ (99m) Tc-MIBI myocardial perfusion imaging. NTG0.6mg was subconjunctivally subcutaneously five minutes prior to intravenous injection of radiopharmaceuticals 48 hours later, and then resting resting myocardial perfusion imaging was performed. Resting myocardial imaging was performed 3 months after coronary artery bypass grafting or percutaneous transluminal coronary angioplasty and compared. Results: There were 113 segments in 16 patients with resting myocardial perfusion imaging with abnormal radioactivity distribution. After NTG intervention, 32 segments improved perfusion, and 25 segments postoperative resting myocardial perfusion also improved. NTG After intervention, no changes or abnormal perfusion of the 81 segments, postoperative 66 segment perfusion also no change or abnormal increase. NTG interventional myocardial tomography prediction of viable myocardium accuracy was 80.5%. Therefore, the inclusion of NTG to improve static ~ (99m) Tc-MIBI myocardial tomography myocardial evaluation of myocardial survival has certain clinical value, and convenient, safe and reliable.