英《Lancet》杂志1982,2:727.哈默斯密斯医院的心脏病学家似已证实血小板在心肌局部缺血的病因方面起着重要的作用.虽然有人在以前提出过这种联系,但是临床研究并没有直接加以肯定. Fox、Jonathan、Selwyn采用了使种血小板聚集的有效抑制剂Ticlopidine,这种抑制剂对血小板膜的改变不同于其他抑制剂的作用方式,例如阿司匹林。经证实心绞痛稳定但在休息和活动时常有心肌局部缺血发作 Lancet Magazine 1982, 2: 727. Cardiologists at Hammersmith Hospital have confirmed that platelets play an important role in the etiology of myocardial ischemia. While some have suggested this association in the past, Clinical studies have not been directly affirmed. Fox, Jonathan, Selwyn used Ticlopidine, a potent inhibitor of platelet aggregation, that changes the platelet membrane differently than other inhibitors, such as aspirin. Confirmed angina pectoris but rest and activity are often myocardial ischemic attack