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目的和方法:对74例住院病人分肠癌组、肠病组、出血与非出血四组,将化学潜血检测(FOB)与SPA免疫潜血试验(SPA)对检测消化道出血的敏感性和特异性进行对比,并将潜血试验与直肠粘液T抗原对大肠癌的诊断价值进行探讨,结果:结果表明T抗原诊断大肠癌阳性预告值100%,阴性预告值为84.6%而SPA诊断大肠癌的阳性预告值及阴性预告值分别为63.2%和80%,证实T抗原对大肠癌的诊断效率(91.7%)极显著高于SPA(66.7%).结论:两种方法联合检测,可提高肠病的检出率,两法同时阳性,恶性病变可能极大.SPA法与FOB法对消化道出血的诊断效率无明显差异,但对消化道出血的特异性,SPA法极显著高于FOB法,FOB法对诊断大肠癌特异性较差,易受饮食、药物等因素干扰,SPB较之有较高的敏感性和特异性,且操作简便、结果判断迅速、重复性好,可作为临床检测消化道出血时推广应用.
PURPOSE AND METHODS: The sensitivity and specificity of FOB and SPA for the detection of gastrointestinal bleeding in 74 inpatients with colon cancer, enteropathy, hemorrhage and non-hemorrhage were studied. Sex, and the occult blood test and rectal mucosal T antigen in the diagnosis of colorectal cancer were discussed, the results show that: T antigen diagnosis of colorectal cancer positive predictive value of 100%, negative predictive value of 84.6% and SPA diagnosis of colorectal cancer positive The predictive value and negative predictive value were 63.2% and 80%, respectively, confirming that the diagnostic efficiency of T antigen for colorectal cancer (91.7%) was significantly higher than that of SPA (66.7%). Conclusion: The combination of the two methods can improve the intestinal disease The detection rate, both positive and malignant lesions may be great.SPA method and FOB method for the diagnosis of gastrointestinal bleeding efficiency no significant difference, but the specificity of gastrointestinal bleeding, SPA method was significantly higher than the FOB method, FOB Law for the diagnosis of colorectal cancer less specific, susceptible to interference by diet, drugs and other factors, SPB compared with higher sensitivity and specificity, and easy to operate, the results of rapid and reproducible, and can be used as a clinical test of the digestive tract Promote the application of bleeding.