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用组织化学方法研究急性镉中毒小鼠睾丸ＬＤＨ－Ｘ活性改变，染镉１ｈ组曲细精管ＬＤＨ－Ｘ活性无明显下降；染镉３ｈ组ＬＤＨ－ｘ活性降低（Ｐ＜０．０５），６及１２ｈ组活性更低，与正常组比差异有显著性（Ｐ＜０．０１）。染镉前以锌保护，染镉１ｈ和３ｈ组ＬＤＨ－Ｘ活性与正常组无明显差异；而６ｈ及１２ｈ组酶活性下降（分别Ｐ＜０．０５，Ｐ＜０．０１），但其ＬＤＨ－Ｘ活性仍显著高于相应时间的镉中毒组（分别Ｐ＜０．０５，Ｐ＜０，０１），提示急性镉中毒可导致睾丸曲细精管ＬＤＨ－Ｘ活性降低，锌对其活性有一定程度的保护作用。
The LDH-X activity in the testis of acute cadmium poisoning mice was studied by histochemical method. LDH-X activity of seminiferous tubules in 1h cadmium-dyed cadmium-treated group was not significantly decreased. LDH-x activity in cadmium dyed group was decreased 3h (P <0.05) And 12h group was lower than that in normal group (P <0.01). The activity of LDH-X in cadiocytes exposed to cadmium for 1 h and 3 h did not show significant difference from that of the normal group, while the activity of LDH-X decreased in the 6 h and 12 h groups (P <0.05 and P <0.01, respectively) -X activity was still significantly higher than the corresponding time of cadmium poisoning group (P <0.05, P <0,01, respectively), suggesting that acute cadmium poisoning can lead to decreased testicular seminiferous tubule LDH-X activity, zinc activity A degree of protection.