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糖尿病酮症酸中毒(diabetic ketoacidosis,DKA)是由于体内的胰岛素缺乏引起的以高血糖、高酮症和代谢性酸中毒为主要改变的临床综合征,是糖尿病(DM)的急性合并症,也是内科常见急症之一。我院1993年3月至今共收治DM患者207例,其中并发DKA 29例(约14％),本文对29例DKA临床分析如下。 1临床资料 1.1一般资料 29例全部为住院患者,其中男12例,女17例,年龄在17～71岁之间(43±11.6)岁,病程4～11年(4.0±2.2年)。Ⅰ型DM 12例,Ⅱ型DM 17例。诱发因素:感染14例(48.3％),饮食不当7例(24.1％),劳累5例(17.4％),原因不明3例(10.3％),胰岛素应用不当9例(31.0％)。 1.2临床表现及实验室检查 食欲减退21例(72.4％),恶心、呕吐15例(51.7％),乏力19例(65.5％),头痛、头晕9例(31.0％)“三多”加重10例(34.5％),腹痛2例(6.9％),倦怠5例(17.4％),昏迷4例(13.8％)。25例症状较轻,尿糖(++～
Diabetic ketoacidosis (DKA) is a clinical syndrome that has been implicated in hyperglycemia, ketosis and metabolic acidosis as a result of insulin deficiency in the body and is an acute complication of diabetes mellitus (DM) One of the common medical emergency. Our hospital since March 1993 had a total of 207 patients with DM, including 29 cases of DKA (about 14%), the 29 cases of DKA clinical analysis of the following. 1 Clinical data 1.1 General Information All 29 cases of hospitalized patients, including 12 males and 17 females, aged 17 to 71 years (43 ± 11.6 years), duration of 4 to 11 years (4.0 ± 2.2 years). 12 cases of type I DM and 17 cases of type II DM. Infectious factors included infection in 14 (48.3%), improper diet in 7 (24.1%), fatigue in 5 (17.4%), unexplained 3 (10.3%) and inappropriate use of insulin in 9 (31.0%). 1.2 clinical manifestations and laboratory tests in 21 cases (72.4%), nausea and vomiting in 15 cases (51.7%), fatigue in 19 cases (65.5%), headache, dizziness in 9 cases (31.0% (34.5%), abdominal pain in 2 cases (6.9%), fatigue in 5 cases (17.4%) and coma in 4 cases (13.8%). 25 cases of mild symptoms, urine sugar (++ ~