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严重腹腔感染是指合并脓毒症与脓毒症休克的腹腔感染。严重腹腔感染多发生于消化道穿孔,破裂和肠吻合口破裂继发性腹膜炎,也可出现在原发与继发性腹膜炎治疗失败后的复发性腹膜炎或持续性腹膜炎及第三型腹膜炎。严重腹腔感染发生时由于短时间内大量细菌与毒素入血,可迅速引起急性炎症反应综合征、休克、急性呼吸窘迫综合征和急性肾功能衰竭,甚至导致死亡。资料显示,外科ICU患者的基础和24h血乳酸水平与预后密切相关[1]。
Severe abdominal infection is associated with sepsis and septic shock of abdominal infection. Serious abdominal infections occur in the perforation of the digestive tract, rupture and rupture of intestinal anastomotic secondary peritonitis, recurrent peritonitis or persistent peritonitis and type 3 peritonitis after primary and secondary peritonitis failure may also occur. Severe abdominal infection occurs due to a large number of bacteria and toxins into the blood within a short time, can rapidly cause acute inflammatory response syndrome, shock, acute respiratory distress syndrome and acute renal failure, and even lead to death. Data show that the basis of surgical ICU patients and 24h blood lactate levels and prognosis are closely related [1].