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目的探讨4000米及以上海拔地区45岁以上人员HBV感染状况及HBV不同模式的检出情况。方法 2008年9月2009年6月对2244名45岁以上人员进行空腹抽血4mL,1h内分离血清,用酶联试剂进行检测。结果对青海省杂多地区45岁以上2244人的个体检查发现,HBsAg(+)阳性病395人,是受检人数的17.6%,HBeAg阳性294人,是受检人数的13.1%,前S1Ag阳性332人,是受检人数的16.0%,检查发现前S1Ag较HBeAg的检出率略高。结论通过对高海拔地区长期生活和工作人员的HBV感染率及感染模式的研究;对地区乙肝的预防和治疗作出评估;应加强乙肝疫苗的接种工作。
Objective To investigate the status of HBV infection and the detection of different patterns of HBV in people above 45 years of age at altitude of 4000 meters and above. Methods September 2008 22,044 45-year-old above 4 people on a fasting blood 4mL, within 1h serum was separated and detected by enzyme-linked reagent. Results A total of 2244 individuals over the age of 45 in He Zuo area of Qinghai Province found that 395 HBsAg positive patients were infected with 17.6% HBsAg positive, 294 HBeAg positive, accounting for 13.1% 332 people, which is 16.0% of the number of subjects examined. The detection rate of S1Ag was slightly higher than that of HBeAg. Conclusions The HBV infection rate and infection pattern of long-term living and working staff in high altitude areas are studied. The prevention and treatment of hepatitis B in the area are evaluated. Vaccination of hepatitis B vaccine should be strengthened.