IgG4相关性疾病是一种慢性、进行性全身系统性免疫性疾病,可累及多种器官及组织,如胰腺、肾脏、腹膜后组织、唾液腺、泪腺、淋巴结等[1,2]。IgG4相关性疾病作为一种近几年新被提出的自身免疫性疾病,对其认识仍不足[3,4]。1资料与方法1.1临床资料患者男,59岁,发现颌下无痛性肿物20余天于口腔科就诊,患者无发热、寒战,无恶心、呕吐,偶有口干。患者一般情况尚可,神志清醒。 IgG4-related diseases are chronic and progressive systemic systemic immune diseases involving various organs and tissues such as the pancreas, kidney, retroperitoneal tissue, salivary gland, lacrimal gland, and lymph nodes [1,2]. IgG4-related diseases, as a newly proposed autoimmune disease in recent years, are still not fully understood [3,4]. 1 Materials and Methods 1.1 Clinical data Male, 59 years old, found submandibular painless pain more than 20 days in the dental treatment, patients without fever, chills, no nausea, vomiting, occasional dry mouth. The general condition of patients, conscious.