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目的分析内镜黏膜下层剥离术(ESD)术后胃溃疡愈合的影响因素。方法收集医院行ESD治疗患者共112例的临床资料,利用logistic回归分析对年龄、性别、是否患有糖尿病、病灶大小、术后溃疡大小、是否有幽门螺杆菌感染及病灶部位进行分析,研究上述因素对ESD术后胃溃疡愈合的影响。结果糖尿病患者溃疡愈合效果较无糖尿病患者明显不佳,位于贲门、胃窦小弯及胃角的病灶溃疡愈合效果较其他部位病灶好。结论糖尿病病史及病灶位置不同对溃疡的愈合产生影响。
Objective To analyze the influencing factors of gastric ulcer healing after endoscopic submucosal dissection (ESD). Methods The clinical data of 112 patients with ESD treated in our hospital were collected. The age, gender, diabetes mellitus, the size of the lesion, the size of the ulcer, the presence of H. pylori infection and the lesion location were analyzed by logistic regression analysis. Effect of Factors on Healing of Gastric Ulcer after ESD Operation. Results The healing effect of ulcer in diabetic patients was obviously worse than that in non-diabetic patients. The healing effect of ulcer on the lesser curvature of stomach and gastric antrum was better than that of other parts. Conclusion The history of diabetes mellitus and the location of the lesion affect the healing of ulcer.