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目的 探讨分析79例双胎出生缺陷情况,为更深层次的了解双胎出生缺陷问题提供参考.方法 根据浙江省出生缺陷监测工作手册的要求,对出生缺陷情况进行监测,采用回顾性分析的方法,搜集2011年10月至2017年6月金华市出生缺陷省级监测点收集的双胎出生缺陷儿的临床资料,以出生缺陷儿为研究组,观察各类出生缺陷发生率及构成比和出生缺陷儿性别情况.结果 各类出生缺陷中,最常见的是先天性心脏病,其次是多指、总唇腭裂,且出生缺陷儿中,男性比例高于女性(P＜0.05).结论 要加大对优生优育的宣传力度,加强对双胎孕产妇的产前筛查与产前诊断,逐步降低双胎出生缺陷儿的比例,更一步提高整体的人口素质.“,”Objective:To analyze the situation of the birth defects in 79 cases and to provide references for further understanding of the birth defects.Methods:According to the requirements of zhejiang birth defects monitoring work manual of birth defects monitoring,adopt the method of retrospective analysis,gathering in October 2011 to June 2017 Jinhua birth defect provincial monitoring point clinical data of birth defects were twins,birth defects,for the team,to observe all kinds of incidence of birth defects and the proportion of gender and birth defects.Results:All kinds of birth defects,the most common was congenital heart disease,followed by multiple fingers,total cleft lip and palate,and the male proportion of birth defects was higher than that of women (P＜0.05).Conclusion:To increase the propaganda of eugenic and superior nurture,strengthen pair of twins maternal prenatal screening and prenatal diagnosis,gradually reduce the proportion of defects were twins,further improve the overall quality of the population.