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本实验采用放射免疫法检测原发性肝癌(PHC)病人血浆内皮素(ET)含量,探讨了ET含量与肝癌病情关系。结果表明:①ET在PHC病人组明显高于肝硬化(LC)组和对照组(NC);②ET与AFP含量呈正相关;③ET在肿瘤直径大于5cm单发组,明显高于直径小于5cm单发组;④肝内转移组,又明显高于无肝内转移组。提示ET与肝癌的发生发展关系密切。
In this experiment, radioimmunoassay was used to detect plasma endothelin (ET) content in patients with primary liver cancer (PHC), and the relationship between ET content and liver cancer condition was discussed. The results showed that: 1ET was significantly higher in the PHC patient group than in the cirrhosis (LC) group and the control group (NC); 2ET was positively correlated with the AFP content; 3ET was greater in the tumor group than the 5cm solitary group, which was significantly higher than the somatic group less than 5cm in diameter. ;4Intrahepatic metastasis group was significantly higher than that without intrahepatic metastasis group. It is suggested that ET is closely related to the occurrence and development of liver cancer.