论文部分内容阅读
目的:通过中性粒细胞碱性磷酸酶(NAP)染色,探讨急性淋巴细胞白血病(ALL)与急性髓细胞白血病(AML)患者NAP的阳性率及积分鉴别诊断的价值,以提高急性白血病诊断的准确性和及时性。方法:应用偶氮偶联法⑴对105例急性白血病,包性急性淋巴细胞白血病(ALL)41例、急性髓系细胞白血病(AML)64例,90例正常对照组进行NAP阳性率及积分进行检测,经统计学分析,算出相关性、特异性及差异性。结果:急性淋巴细胞白血病NAP阳性率和积分比急性髓性白血病、正常对照组明显增高,有显著差异(P<0.01);急性髓性白血病比急性淋巴细胞白血病、正常对照组明显降低,有显著差异(P<0.01)。结论:NAP对急性白血病有重要的鉴别作用。
Objective: To investigate the positive rate of NAP in patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) by neutrophil alkaline phosphatase (NAP) staining and the value of differential diagnosis in order to improve the diagnosis of acute leukemia Accuracy and timeliness. Methods: Azo-conjugate method was used to detect NAP positive rate and integral in 105 cases of acute leukemia, 41 cases of acute lymphoblastic leukemia (ALL), 64 cases of acute myeloid leukemia (AML) and 90 cases of normal control group Detection, the statistical analysis to calculate the relevance, specificity and diversity. Results: The positive rate and integral of NAP in acute lymphoblastic leukemia were significantly higher than those in acute myeloid leukemia and normal control group (P <0.01). Acute myeloid leukemia was significantly lower than that in acute lymphoblastic leukemia and normal control group Difference (P <0.01). Conclusion: NAP has an important role in the differential diagnosis of acute leukemia.