论文部分内容阅读
目的探讨乙型病毒性肝炎与原发性肝细胞癌的相关性进行研究。方法将本院2008年1月至2009年1月收治的原发性肝癌248例,进行肝炎病毒指标研究包括乙肝5项(HBsAg、抗-HBs、HBeAg、抗-HBe、抗-HBc),甲胎蛋白(AFP)检测。结果HBV感染196例,占248例原发性肝癌79.03%。结论HBV感染是导致原发性肝癌主要病因。HBsAg(+)AFP升高82.14%,HBsAg(-)AFP升高23.07%,可能是由于乙型病毒感染HBV复制造成的肝细胞损伤,随之发生的肝细胞再生和修复,促进了AFP合成增加[6],是造成HBsAg(+)和HBsAg(-)患者血清水平显著差异的重要原因。
Objective To investigate the relationship between hepatitis B and primary hepatocellular carcinoma. Methods A total of 248 patients with primary liver cancer admitted to our hospital from January 2008 to January 2009 were enrolled in this study. Five hepatitis B virus markers (HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc) Fetoprotein (AFP) test. Results 196 cases of HBV infection, 248 cases of primary liver cancer 79.03%. Conclusion HBV infection is the main cause of primary liver cancer. The increase of HBsAg (+) AFP by 82.14% and the increase of HBsAg (-) AFP by 23.07% were probably due to hepatocellular injury caused by HBV replication of HBV and consequent hepatocyte regeneration and repair, which promoted the increase of AFP synthesis [6] is a significant cause of significant differences in serum levels of HBsAg (+) and HBsAg (-) patients.