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目的 探讨脑深部STN刺激靶点时MRI直接定位法和MER术中导引定位法的解剖学偏差。方法 本组5例帕金森病患者,分别表现为运动迟缓、步态不稳及躯干症状,共安放6例次微电极。结果 采用MRI直接定位法和MER术中导引定位法,其定位靶点的平均偏差距离是1.25mm,尽管该偏差值较小,但是,基于影像学的立体定向法只能将刺激电极定位于距离靶点几毫米的范围内。结论 电生理学方法（MER）对于调整和确定靶点位置至关重要。MER术中导引定位法有助于手术的完全成功。
Objective To investigate the anatomical deviations of the direct MRI method and the MERO guided positioning method in deep brain stimulation of STN. Methods Five patients with Parkinson’s disease in our group were presented with motionlessness, unstable gait and trunk symptoms respectively. Six sub-microelectrodes were placed in this group. Results The direct MRI method and the MER-guided method showed that the average distance between the target and the target was 1.25mm. Although the deviation was small, the imaging-based stereotactic method could only locate the stimulation electrode Within a few millimeters of the target. Conclusion Electrophysiological methods (MER) are crucial for adjusting and determining the location of a target. MER surgery guided positioning method to help the complete success of surgery.