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一般肌内注射无效或无显著升压作用的盐酸肾上腺素,注射于家兔裂唇内侧上部时产生显著的升压作用,这一部位对肾上腺素特高的感受性,不被普鲁卡因局部浸润所取消或减弱,亦不受戊巴比妥钠全身麻醉所影响,裂唇注射肾上腺素迅速发生的显著升压作用与同量药物肌内注射相比,似具有收缩局部血管以外的局部作用。经利血平处理的家兔,上述部位的显著升压作用不仅保持,而甚增强;静脉内注射乙酰普吗嗪或麦角毒能非常显著地减低肾上腺素于裂唇内侧上部注射时特强的升压作用。
General intramuscular injection of ineffective or no significant role in the role of vasopressin hydrochloride injection in the upper part of the rabbit’s labial lip produces a significant step-up effect, this part of the adrenaline extraordinarily high sensitivity, not by procaine local Infiltration was abolished or weakened, and was not influenced by general anesthesia with sodium pentobarbital. The rapid vasopressin action induced by split lip injection of epinephrine appeared to have a local effect other than contracting local blood vessels compared with the same amount of intramuscular injection . The reserpine-treated rabbits not only retained but significantly boosted the above-mentioned site, and intravenous injection of acetopromate or ergosteroid significantly reduced the effect of epinephrine on the superior medullary injection of the split lip Boost effect.