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成人复发性急性白血病治疗相当困难,且缓解时间短。为此,我们近年设计了用中剂量氨甲喋呤(MTX)、阿糖胞苷(Ara-C)治疗成人复发性急性白血病13例,取得了一定疗效,小结如下。对象与方法病例选择 13例病人均在我院使用 HOAP 或COAP 方案初治取得了完全缓解(CR),且定期用原方案巩固治疗。其中急淋(ALL)4例;急非淋(AN-LL)9例。男8例,女5例。年龄在18～52岁。4例ALL 缓解1～2年后复发者3例,缓解6月后复发
Treatment of adult recurrent acute leukemia is quite difficult, and the remission time is short. To this end, we designed in recent years with the dose of methotrexate (MTX), cytarabine (Ara-C) in the treatment of adult recurrent acute leukemia in 13 cases, and achieved a certain effect, are summarized as follows. Subjects and methods Case selection 13 patients in our hospital with HOAP or COAP regimen achieved complete remission (CR), and regular consolidation of the original treatment. Among them, 4 cases were acute lymphocytic leukemia (ALL) and 9 cases were AN-LL. 8 males and 5 females. The age of 18 to 52 years old. 4 cases of ALL ease 1 to 2 years after relapse in 3 cases, ease the recurrence in June