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γ-氨基丁酸(GABA)是脑内主要的抑制性神经递质,在大脑皮层神经细胞培养中已得到证实。大量研究结果证明,任何导致脑内GABA系统不足的因素,均使动物惊厥阈值下降。我们既往的工作发现,北京医科大学裴印权等培育的遗传性惊厥易感大鼠P_(77)PMC,在生后20～30天时对人工高温诱发惊厥的易感
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the brain that has been demonstrated in neuronal cultures of the cerebral cortex. Numerous studies have shown that any factor that leads to deficient GABA systems in the brain decreases the threshold for convulsions in animals. Our previous work found that P 77 PMC in genetic convulsion-induced seizure induced by Pei Yinquan in Beijing Medical University was susceptible to artificial convulsions induced by artificial hyperthermia at 20-30 days after birth