随着胺碘酮在临床上广泛应用,发现其可引起多种副作用,少数病例可发生急性肝炎和类似酒精性肝病的慢性肝损害,其超微结构特征是肝脏和其他器官的溶酶体内可见磷脂沉积的髓磷脂征。为了解磷脂沉积和假性酒精性肝病之间的关系,作者等对13例接受胺碘酮治疗者的肝活检标本进行光镜和电镜研究,其中4例作了X线微量分析,以发现肝组织中含碘的胺碘酮。 13例心律失常或心绞痛者,胺碘酮的剂 Amiodarone is widely used clinically and has been shown to cause many side effects. In a minority of cases, chronic liver damage can occur in acute hepatitis and alcohol-like liver disease. Its ultrastructural features are visible in the lysosomes of the liver and other organs Phospholipid deposition of myelin sign. To understand the relationship between phospholipid deposition and Pseudoalcoholic Hepatic Disease, the authors performed microscopic and electron microscopic studies on 13 liver biopsy specimens from patients undergoing amiodarone treatment. Four of these patients underwent X-ray microanalysis to find that the liver Iodine containing iodine in tissues. 13 cases of arrhythmia or angina, amiodarone agents