目的　评价乳酸司氟沙星葡萄糖注射液治疗细菌性感染的临床疗效。方法　 4 1例病人 ,分为治疗组 2 1例和对照组2 0例 ,分别应用乳酸司氟沙星葡萄糖注射液和氧氟沙星注射液 ,剂量分别为 0 .2g,qd和 0 .2g ,q12h ,iv ,疗程 7～ 14d。结果　乳酸司氟沙星和氧氟沙星的临床有效率分别为 85 .71%和 85 .0 % ,细菌清除率分别为 72 .73%和 77.78% ,两组不良反应发生率分别为 9.5 2 %和 5 .0 % ,试验中未见光敏反应及其他严重不良反应。结论　乳酸司氟沙星葡萄糖注射液可作为治疗细菌性感染有效、安全的抗菌素 Objective To evaluate the clinical efficacy of lactofloxacin and glucose injection in the treatment of bacterial infections. Methods 41 patients were divided into treatment group 21 cases and control group 20 cases were applied lactofloxacin lactate dextrose injection and ofloxacin injection, the dose was 0.2g, qd and 0.2g , q12h, iv, treatment 7 ~ 14d. Results The clinical effective rates of lefloxacin lactate and ofloxacin were 85.71% and 85.0% respectively, the bacterial clearance rates were 72.73% and 77.78% respectively. The incidence of adverse reactions in both groups were 9.5 2 % And 5.0%, no photosensitive test and other serious adverse reactions. Conclusions Lifloxacin lactate dextrose injection can be used as an effective and safe antibiotic for the treatment of bacterial infections