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目的探讨间断蓝光照射治疗新生儿高胆红素血症的可行性。方法将66例高胆红素血症患儿随机分为两组。观察组36例,对照组30例,两组在日龄、体重、性别、黄疸程度差异无统计学意义。观察组采用间断蓝光照射,每天照射8～12h,对照组采用持续蓝光照射,2～3d为1个疗程,中间休息1d,再重复应用,将所得的结果、副作用发生率,进行统计学处理。结果间断蓝光照射与持续蓝光照射对新生儿高胆红素血症同等有效(P>0.05)。持续蓝光照射比间断蓝光照射副作用发生率高。如皮疹、发热、腹泻、轻度脱水、精神疲乏、吮乳能力下降出现率高于后者(P<0.05)。结论间断蓝光照射治疗新生儿高胆红素血症优于持续蓝光照射。
Objective To investigate the feasibility of intermittent blue light irradiation in the treatment of neonatal hyperbilirubinemia. Methods 66 cases of hyperbilirubinemia were randomly divided into two groups. 36 cases in the observation group and 30 cases in the control group. There was no significant difference in the age, body weight, gender and jaundice between the two groups. The observation group received intermittent blue light irradiation for 8 to 12 hours daily. The control group received continuous blue light irradiation for 2 to 3 days for 1 course of treatment and the rest for 1 day. The results were repeated and the incidence of side effects was statistically analyzed. Results Intermittent blue light and continuous blue light were equally effective in neonatal hyperbilirubinemia (P> 0.05). Continuous blue light irradiation than intermittent blue light incidence of high incidence. Such as rash, fever, diarrhea, mild dehydration, mental fatigue, decreased sucking ability was higher than the latter (P <0.05). Conclusion Intermittent blue light irradiation is superior to continuous blue light irradiation in neonatal hyperbilirubinemia.