原发性脾何杰金病临床类型较特殊,其确诊有别于临床常见的淋巴瘤。我院曾收治一例,现报告如下。患者男,45岁。浙江籍,已婚,农民。起因于原因不明的午后发热,伴脾肿大2月余,于1990年6月20日入院。患者入院前两个月呈现无明显诱因体温升高,每日下午明显(T38℃),无畏寒、盗汗、咳嗽,经抗炎治疗(氟哌酸,头孢唑啉钠)效果不佳。查体:发育正常,体重58 kg,营养中等,咽无充血,扁桃体无肿大,全身浅表淋巴结未触及,心、肺无异常发现,肝肋下刚及,脾肋下2.5 cm,质中,无触痛,腹壁未见静脉怒张,无腹水。实验室检查:Hb 120 g/L,Plt113×10~9/L,WBC2.6×10~9/L,N0.64,L0.32,M0.04。骨髓像:有核细胞中等量,粒系增生活跃,以中幼粒细胞以下阶段增生为主,少数粒细胞胞浆中有少量空泡,红系增生 Hodgkin’s disease of primary spleen clinical type is rather special, its diagnosis is different from the common clinical lymphoma. Our hospital has admitted a case, the report is as follows now. Male patient, 45 years old. Zhejiang membership, married, farmers. Due to unexplained afternoon fever, with splenomegaly more than 2 months, in June 20, 1990 admission. Two months before admission, there was no obvious incentive for the body temperature to rise. Every day afternoon obviously (T38 ℃), no chills, night sweats and cough. The anti-inflammatory treatment (norfloxacin and cefazolin sodium) was not effective. Physical examination: normal development, weight 58 kg, moderate nutrition, no pharynx congestion, tonsil enlargement, systemic superficial lymph nodes not touched, heart, lung no abnormalities found, liver ribs just below, spleen rib 2.5 cm, , No tenderness, no abdominal vein engorgement, no ascites. Laboratory tests: Hb 120 g / L, Plt113 × 10 ~ 9 / L, WBC2.6 × 10 ~ 9 / L, N0.64, L0.32, M0.04. Bone marrow: nucleated cells in the same amount, active hyperplasia granulocyte, mainly in the following stages of myeloid hyperplasia, a small number of cytoplasm in a small number of vacuoles, erythroid hyperplasia