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非心血管系药物一、三环类抗抑郁药如丙米嗪、阿米替林、多虑平等。可引起心血管系统副作用的中枢神经系统药物很多,而三环类抗抑郁药是比较重要的。据报道,此类药物即使用治疗量,亦约有20%的病人可出现心电图异常,如Q-T间期延长,S-T段压低,T波平坦,右束枝传导阻滞等。进一步则可发生各种严重的心律失常,如房性或多源性早搏,室性或室上性心动过速、房扑、房颤、室颤等。对原有心疾患的患者,甚至可能引起突然死亡。一般认为上述副作用的发生是由于此类药
Non-cardiovascular drugs, tricyclic antidepressants such as imipramine, amitriptyline, more anxiety. There are many central nervous system drugs that can cause cardiovascular system side effects, while tricyclic antidepressants are more important. It is reported that such drugs that use the amount of treatment, about 20% of patients also have ECG abnormalities, such as Q-T interval prolongation, S-T depression, T wave flat, right bundle branch block and so on. Further can occur a variety of serious arrhythmia, such as atrial or multi-source premature beats, ventricular or supraventricular tachycardia, atrial flutter, atrial fibrillation, ventricular fibrillation and so on. Patients with existing heart disease may even cause sudden death. Generally believed that the occurrence of these side effects is due to such drugs