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目的浅析幽门螺杆菌与消化性溃疡的临床相关性。方法选择2014年7月至2015年7月在我院门诊检查为消化性溃疡的200例患者资料,所有的患者经过胃镜检查、Warthin-starry法和快速尿激酶检测法均确诊溃疡组织中有幽门螺杆菌,分析幽门螺杆菌与消化性溃疡的相关性。结果 200例患者中幽门螺杆菌为阳性的患者为135例,阳性率为65.0%;男性患者中幽门螺杆菌阳性率为71.9%,显著高于女性患者,差异具有统计学意义(P<0.05);在所有的年龄段患者中,30~50岁幽门螺杆菌阳性率最高幽门螺杆菌阳性率最高,十二指肠溃疡患者幽门螺杆菌阳性率显著高于胃溃疡患者,差异具有统计学意义(P<0.05)。结论幽门螺杆菌感染是引发消化性溃疡的重要原因,对幽门螺杆菌进行清除可以有效治疗消化性溃疡,从而提高患者生活质量。
Objective To analyze the clinical correlation between Helicobacter pylori and peptic ulcer. Methods From July 2014 to July 2015 in our hospital outpatient examination for peptic ulcer in 200 patients, all patients after gastroscopy, Warthin-starry method and rapid urokinase test were confirmed ulcer tissue in the pylorus Helicobacter, Analysis of Helicobacter pylori associated with peptic ulcer. Results The positive rate of Helicobacter pylori in 200 patients was 135 and the positive rate was 65.0%. The positive rate of Helicobacter pylori in male patients was 71.9%, which was significantly higher than that in female patients (P <0.05) ; In all age groups, the highest positive rate of Helicobacter pylori 30 to 50 years old was the highest, the positive rate of Helicobacter pylori in patients with duodenal ulcer was significantly higher than that in patients with gastric ulcer, the difference was statistically significant ( P <0.05). Conclusion Helicobacter pylori infection is an important cause of peptic ulcer. Helicobacter pylori eradication can effectively treat peptic ulcer and improve the quality of life of patients.