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目的探讨国产α－氰基丙烯酸正丁酯（ＮＢＣＡ）栓塞治疗脑动静脉畸形（ＡＶＭ）的适应证、技术要点、栓塞剂的配制及术后并发症。方法４０例病人应用微导管插管技术，在数字减影血管造影（ＤＳＡ）监视下，对畸形血管团进行血管内栓塞治疗。结果栓塞５７次，治愈８例，临床症状明显好转３１例，另１例死于其它疾病，无再出血病例。并发症主要为头痛、神经功能障碍及正常灌注压突破（ＮＰＰＢ），１例ＮＰＰＢ开颅清除血肿并切除畸形灶，１例视野缺损未恢复，其他经对症处理后均痊愈。结论ＮＢＣＡ血管内栓塞治疗脑ＡＶＭ是一种有效的治疗方法。国产ＮＢＣＡ性能良好，安全可靠，价格低廉，可代替进口产品。
Objective To investigate the indications, technical points, preparation of embolic agents and postoperative complications of cerebral arteriovenous malformations (AVM) treated with n-butyl α-cyanoacrylate (NBCA) in China. Methods 40 patients underwent microcatheter catheterization under endovascular digital embolization (DSA) monitoring. Results embolization 57 times, 8 cases were cured, clinical symptoms were significantly improved in 31 cases, the other died of other diseases, no rebleeding cases. The main complications were headache, neurological dysfunction and normal perfusion pressure breakthrough (NPPB). One NPPB craniotomy cleared the hematoma and removed the deformity lesion. One case of visual field defect did not recover and the others recovered after symptomatic treatment. Conclusion NBCA endovascular embolization of brain AVM is an effective treatment. Domestic NBCA good performance, safe, reliable, low prices, can replace imported products.