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目的对2015年我院抗菌药物的使用情况进行统计,分析各类抗菌药物的特点和用药趋势,为其科学管理及合理用药提供参考。方法采用WHO推荐的限定日剂量(DDD)作为测定药物的利用单位,通过用药频度(DDDs)分析用药情况。根据药品用量、销售金额和DDDs,并结合细菌耐药性对抗菌药物的使用特点进行总结和分析。结果 2015年我院抗菌药物从单药DDDs值上看,克拉霉素缓释片、头孢哌酮/舒巴坦针剂、替硝唑片、头孢硫脒针、比阿培南针排名靠前,从院感细菌药物敏感结果显示,常见院感细菌对常用抗菌药物的耐药性仍较严重。结论加强抗菌药物管理必须结合细菌耐药性情况,尽量减少抗菌药物的滥用,提高合理用药水平,以达到安全、有效、经济用药的目的。
Objective To analyze the use of antibacterials in our hospital in 2015, and to analyze the characteristics and medication trends of various antibacterials, and to provide a reference for their scientific management and rational drug use. Methods DDD, recommended by the WHO, was used as the unit for the determination of drug use, and drug use was analyzed by DDDs. According to the amount of drugs, the amount of sales and DDDs, combined with bacterial resistance characteristics of antibacterial drugs were summarized and analyzed. Results In our hospital, in 2015, the DDDs of clarithromycin, cefoperazone / sulbactam, tinidazole tablets, cefathiamidine needle and biapenem top ranked first in terms of single drug DDDs. Susceptibility of nosocomial bacterial drugs showed that common nosocomial bacteria were more resistant to common antibacterials. Conclusion To strengthen the management of antimicrobial agents, bacterial resistance must be combined to minimize the abuse of antimicrobial agents and improve the rational use of drugs in order to achieve safe, effective and economical use of drugs.