论文部分内容阅读
从ＩＣＵ患者的临床标本中共分离到１１４株细菌，其中Ｇ－杆菌占９０．４％，主要是铜绿假单胞菌（３２．５％）、硝酸盐阴性不动杆菌（２４．６％）和产黄菌属（１４．０％）及肺炎克雷白菌（７．０％）。测定了１６种抗生素对１０２株Ｇ－杆菌的ＭＩＣ，发现除６株奇异变形杆菌和３株哈夫尼亚菌外，均对１６种抗生素呈不同程度的耐药性，多数对５种以上抗生素同时耐药，最多的达１２种。１６种抗生素中，伊米配能除对产黄菌外的各种Ｇ－杆菌最为敏感，耐药率最低；头孢他定、环丙沙星和哌拉西林其次；而头孢唑啉耐药率达９３．１％，二代头孢菌素和氨苄青霉素也达６０％以上，但头孢西丁对产黄菌属作用最优。
A total of 114 strains of bacteria were isolated from clinical samples of patients with ICU, of which 90.4% were G-bacteria, mainly Pseudomonas aeruginosa (32.5%), nitrate-negative Acinetobacter (24.6%) and Flavobacterium (14.0%) and Klebsiella pneumoniae (7.0%). The MICs of 16 antibiotics against 102 strains of G-bacteria were determined and found that 16 strains of antibiotics were resistant to various degrees except for 6 strains of Proteus mirabilis and 3 strains of Hafnia, most of which were resistant to more than 5 antibiotics Resistance at the same time, up to 12 species. Of the 16 kinds of antibiotics, imipenem was the most sensitive to all kinds of G-bacilli except xanthophyll, with the lowest rate of resistance; ceftazidime, ciprofloxacin and piperacillin followed by cefazolin resistance rate Up to 93.1%, second-generation cephalosporins and ampicillin also reached more than 60%, but cefoxitin on the production of the best role of genus.