胃癌是消化系统常见的恶性肿瘤之一,大多数患者诊疗时已处于疾病晚期,近10余年来晚期胃癌的治疗没有重大突破,化疗的有效率较低,中位生存期7~9个月,2年生存率<10%[1]。针对肿瘤细胞生长及血管生成等靶点的分子靶向治疗是目前进展期胃癌治疗领域研究的热点。本文简要概述表 Gastric cancer is one of the most common malignant tumors in the digestive system. Most patients are already diagnosed with advanced disease. In the past 10 years, there has been no major breakthrough in the treatment of advanced gastric cancer. Chemotherapy is less effective and has a median survival of 7 to 9 months. 2-year survival rate <10% [1]. Targeted molecular targets such as tumor cell growth and angiogenesis are hot topics in the field of advanced gastric cancer treatment. This article is a brief overview of the table