The lithofacies palaeogeography of the Late Permian Wujiaping Age in Middle and Upper Yangtze Region was studied based on petrography and the “single factor analysis and multifactor comprehensive mapping” method.The Upper Permian Wujiaping Stage in the Middle and Upper Yangtze Region is mainly composed of carbonate rocks and clastic rocks,with lesser amounts of siliceous rocks,pyroclastic rocks,volcanic rocks and coal.The rocks can be divided into three types,including clastic rock,clastic rock-limestone and limestone-siliceous rock,and four fundamental ecological types and four fossil assemblages are recognized in the Wujiaping Stage.Based on a petrological and palaeoecological study,six single factors were selected,namely,thickness(m),content(%) of marine rocks,content(%) of shallow water carbonate rocks,content(%) of biograins with limemud,content(%) of thinbedded siliceous rocks and content(%) of deep water sedimentary rocks.Six single factors maps of the Wujiaping Stage and one lithofacies palaeogeography map of the Wujiaping Age were composed.Palaeogeographic units from west to east include an eroded area,an alluvial plain,a clastic rock platform,a carbonate rock platform where biocrowds developed,a slope and a basin.In addition,a clastic rock platform exists in the southeast of the study area.Hydrocarbon source rock and reservoir conditions were preliminarily analyzed based on lithofacies palaeogeography.Sedimentary environments have obvious controls over the development of the resource rocks.With regard to the abundance of organic matter,the hydrocarbon potential of the coastal swamp environment is the best,followed by the basin environment and the carbonate rock platform.The gas reservoir types of the Wujiaping Stage can be classified as conventional and unconventional gas reservoirs,like coal bed gas and shale gas.all of them have well exploration prospects. The lithofacies palaeogeography of the Late Permian Wujiaping Age in Middle and Upper Yangtze Region was studied based on petrography and the “single factor analysis and multifactor comprehensive mapping ” method. The Upper Permian Wujiaping Stage in the Middle and Upper Yangtze Region is mainly composed of carbonate rocks and clastic rocks, with lesser amounts of siliceous rocks, pyroclastic rocks, volcanic rocks and coal. These rocks can be divided into three types, including clastic rock, clastic rock-limestone and limestone-siliceous rock, and four fundamental ecological types and four fossil assemblages are recognized in the Wujiaping Stage. Based on a petrological and palaeoecological study, six single factors were selected, namely, thickness (m), content (%) of marine rocks, content content (%) of biograins with limemud, content (%) of thinbedded siliceous rocks and content (%) of deep water sedimentary rocks.Six single factors maps of the Wujiaping Stage and one lithofacies palaeogeography map of the Wujiaping Age were composed. Palaeogeographic units from west to east include an eroded area, an alluvial plain, a clastic rock platform, a carbonate rock platform where biocrowds developed, a slope and a basin. platform exists in the southeast of the study area. Hydrocarbon source rock and reservoir conditions were preliminished based on lithofacies palaeogeography. edimentary environments have obvious controls over the development of the resource rocks.With regard to the abundance of organic matter, the hydrocarbon potential of the coastal swamp environment is the best, followed by the basin environment and the carbonate rock platform. The gas reservoir types of the Wujiaping Stage can be classified as conventional and unconventional gas reservoirs, like coal bed gas and shale gas. all of them have well exploration prospects.