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作者对31例大肠癌手术标本的肿瘤组织或转移的淋巴结中的肿瘤进行短期微量组织培养,利用闪烁计数器测定~3H-TdR被细胞摄取量的多少来筛选抗癌药物。所得结果表明:不同的病理类型对抗癌药物敏感性有差异,氟尿脱氧核苷、丝裂霉素和氟尿嘧啶可作为大肠癌病人术后首选抗癌药物,并且
The authors carried out short-term micro-cultures of tumors in 31 cases of colorectal cancer surgical specimens or metastatic lymph nodes, and used scintillation counters to measure the amount of ~3H-TdR taken up by cells to screen for anti-cancer drugs. The results showed that: different pathological types of anti-cancer drugs have different susceptibility, fluorouric acid deoxynucleotide, mitomycin and fluorouracil can be used as the first choice for anti-cancer drugs in patients with colorectal cancer, and