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克拉霉素用水溶性羟丙甲纤维素等药用辅料制成缓释片 ,再包薄膜衣用于改善味觉和减小胃肠道副作用。药动学研究证明 ,该制剂与普通片相比具有统计学上显著较低的Cmax、相同的Cmin和AUC ;与美国AbbottLaboratories上市的Bianxing XL片生物等效。
Clarithromycin with water-soluble hypromellose and other pharmaceutical excipients made of sustained-release tablets, and then film-coated for improving the taste and reduce gastrointestinal side effects. Pharmacokinetic studies have shown that this formulation has a statistically significantly lower Cmax, the same Cmin and AUC compared to plain tablets; it is bioequivalent to the Bianxing XL tablets marketed by the U.S. Abbott Laboratories.