妊娠期糖尿病及糖耐量受损的妊娠结局

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目的:探讨妊娠期糖尿病(GDM)及糖耐量受损的临床特点及治疗。方法:回顾性分析三亚市人民医院2008年10月~2009年10月收治的62例妊娠期糖尿病孕妇(GDM组)及52例妊娠期糖耐量受损孕妇(GIGT组)的临床资料,同期随机选择糖筛查正常的孕妇65例作为对照组,比较3组孕妇的妊娠结局和新生儿结局。结果:①GDM组与GIGT组孕妇妊高征、羊水过多、胎儿窘迫、FGR、巨大儿、早产及手术产率均高于对照组;胎膜早破GDM组与对照组比较显著增高,而胎膜早破GIGT组与对照组比较无统计学差异。②GDM组与GIGT组新生儿低血糖、新生儿低血钙、高胆红素血症及新生儿转科率均高于对照组,新生儿窒息GDM组与GIGT组比较显著增高,而新生儿窒息GIGT组与对照组比较无统计学差异。结论:GDM、GIGT均是影响孕妇及围生儿结局的重要因素,对妊娠期不同程度糖耐量异常,应进行监测及处理。 Objective: To investigate the clinical features and treatment of gestational diabetes mellitus (GDM) and impaired glucose tolerance. Methods: The clinical data of 62 pregnant women with gestational diabetes mellitus (GDM group) and 52 pregnant women with impaired glucose tolerance (GIGT group) who were treated in Sanya People’s Hospital from October 2008 to October 2009 were retrospectively analyzed. Randomized Select the normal screening of sugar in pregnant women, 65 cases as a control group, comparing the pregnancy outcome of 3 groups of pregnant women and neonatal outcomes. Results: ①Pregnancy-induced pregnancy induced hypertension, polyhydramnios, fetal distress, FGR, macrosomia, preterm labor and surgical yield were higher in GDM group and GIGT group than those in control group; GDM group and GIGT group were significantly higher than those in control group There was no significant difference between premature rupture of membranes in GIGT group and control group. Neonatal hypoglycemia, neonatal hypocalcemia, hyperbilirubinemia and neonatal morbidity were higher in GDM group and GIGT group than those in control group. Neonatal asphyxia GDM group was significantly higher than GIGT group, while neonatal asphyxia There was no significant difference between GIGT group and control group. Conclusion: Both GDM and GIGT are important factors influencing the outcome of pregnant women and perinatal children. The abnormal glucose tolerance in different stages of pregnancy should be monitored and treated.
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