当应用外用制剂时,如在皮膚上敷用軟膏、乳膏等,可以产生局部的或全身的作用。因此药物自赋形剂或基質中釋放出来的速度和量有很重大的意义。由于外用制剂的賦形剂很多,就需要有适当的方法来評定药物从賦形剂中放出的速度和数量以及透入皮膚后为机体吸收的程度。 When applying topical preparations, such as applying ointment, cream and the like to the skin, it may produce a local or systemic effect. Therefore, the rate of release of the drug from the excipient or matrix is ​​of great importance. Due to the large amount of topical excipients, there is a need for appropriate methods for assessing the rate and amount of drug released from the excipients and the degree of absorption into the body after penetration into the skin.