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我们测定了54例轮状病毒肠炎患儿的红细胞超氧化物歧化酶(SOD)活性及血浆脂过氧化物分解产物丙二醛(MDA)含量,进行动态观察,并与30例正常婴幼儿进行了对照。结果显示,轮状病毒肠炎患儿极期SOD活性明显下降,MDA显著上升。恢复期SOD活性升高,MDA下降。红细胞SOD与血浆MDA同轮状病毒肠炎的病情程度无一定关系。本文提示自由基参与了轮状病毒肠炎的病理过程。
We measured the activity of erythrocyte superoxide dismutase (SOD) and the content of malondialdehyde (MDA) in plasma of 54 children with rotavirus enteritis and observed them dynamically with 30 normal infants A comparison. The results showed that rotavirus enteritis in patients with extreme stage SOD activity decreased significantly, MDA increased significantly. Recovery during the activity of SOD increased MDA decreased. Erythrocyte SOD and plasma MDA with rotavirus enteritis severity has no relationship. This article suggests that free radicals are involved in the pathological process of rotavirus enteritis.